Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25703862 | 0.79 | SCN1A (0.35) | CNR1S1PR1PIK3CDCNR2S1PR3 | |
| SCHEMBL30438685 | 0.79 | SCN1A (0.35) | CNR1S1PR1PIK3CDCNR2S1PR3 | |
| SCHEMBL31294361 | 0.77 | PIK3CD (0.33) | CNR1PIK3CDPIK3CGMAPTALDH1A1 | |
| SCHEMBL31529503 | 0.76 | TP53 (0.36) | S1PR1CNR2MAPTKDM1AGABRB1 | |
| SCHEMBL30438675 | 0.76 | TP53 (0.36) | S1PR1CNR2MAPTKDM1AGABRB1 | |
| SCHEMBL25268013 | 0.74 | SCN1A (0.33) | CNR1S1PR1CNR2S1PR3KDM1A | |
| SCHEMBL25219722 | 0.74 | SCN1A (0.33) | CNR1S1PR1CNR2S1PR3KDM1A | |
| SCHEMBL31180637 | 0.73 | CNR2 (0.36) | CNR1S1PR1CNR2SCN1ASCN5A | |
| SCHEMBL31294322 | 0.72 | PIK3CG (0.37) | PIK3CDPIK3CGALDH1A1 | |
| SCHEMBL31529513 | 0.72 | CNR1 (0.35) | CNR1S1PR1CNR2ALDH1A1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719597-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED CALCIUM ION CHANNEL CAV2.3 ANTAGONISTS | Lario Therapeutics Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246523-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED CALCIUM ION CHANNEL CAV2.3 ANTAGONISTS | LARIO THERAPEUTICS LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |