Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.31 |
| ▸ | FEN1 | P39748 | 5/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.30 |
| ▸ | F9 | P00740 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25703862 | 1.00 | SCN1A (0.35) | SCN1ASCN5ASCN8ARPS6KB1CNR1 | |
| SCHEMBL25701645 | 0.90 | TGFBR1 (0.38) | SCN1ASCN5ASCN8APIK3CDALOX5AP | |
| SCHEMBL30438339 | 0.90 | TGFBR1 (0.38) | SCN1ASCN5ASCN8APIK3CDALOX5AP | |
| SCHEMBL31529538 | 0.89 | TEAD1 (0.34) | PIK3CDS1PR1 | |
| SCHEMBL31294485 | 0.79 | CNR1 (0.36) | SCN1ASCN5ASCN8ACNR1KDM1A | |
| SCHEMBL25219722 | 0.78 | SCN1A (0.33) | SCN1ASCN5ASCN8ACNR1KDM1A | |
| SCHEMBL30438675 | 0.78 | TP53 (0.36) | SCN1ASCN5ASCN8AKDM1AS1PR1 | |
| SCHEMBL25268013 | 0.78 | SCN1A (0.33) | SCN1ASCN5ASCN8ACNR1KDM1A | |
| SCHEMBL31529503 | 0.78 | TP53 (0.36) | SCN1ASCN5ASCN8AKDM1AS1PR1 | |
| SCHEMBL30438623 | 0.77 | DPP4 (0.34) | CNR1PIK3CDKCNH2F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436955-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | Lario Therapeutics Limited (GB) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |