SCHEMBL31294857

SCHEMBL31294857

NC(=O)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 14/20 0.52
▸ ACE2 Q9BYF1 6/20 0.51
▸ CALCRL Q16602 4/20 0.49
▸ OPRM1 P35372 1/20 0.47
▸ OPRD1 P41143 1/20 0.47
▸ RAMP1 O60894 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29592679 0.86 OPRM1 (0.53) CALCRLOPRM1OPRD1RAMP1
SCHEMBL31564847 0.86 OPRM1 (0.57) CALCRLOPRM1OPRD1
SCHEMBL30066883 0.84 ACE (0.55) ACEACE2CALCRLOPRM1OPRD1
SCHEMBL29947679 0.83 ACE (0.42) ACEACE2CALCRL
SCHEMBL30608507 0.83 ACE (0.53) ACEACE2OPRM1OPRD1
SCHEMBL30608506 0.83 ACE (0.53) ACEACE2OPRM1OPRD1
SCHEMBL30785955 0.83 ACE (0.56) ACEACE2OPRM1OPRD1
SCHEMBL29589786 0.82 ACE (0.56) ACEACE2
SCHEMBL29666705 0.82 ACE (0.57) ACEACE2OPRM1OPRD1
SCHEMBL29666878 0.82 ACE (0.58) ACEACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735021-A1 COMBINATION THERAPY Zealand Pharma A/S (DK) 2026-05-06 — — EP disclosed
EP-4731239-A1 ANALOGUES WITH IMPROVED PROPERTIES Zealand Pharma A/S (DK) 2026-04-29 — — EP disclosed
WO-2025229200-A1 MANUFACTURE OF DISULFIDE BONDED PEPTIDES BACHEM HOLDING AG (CH) 2025-11-06 — — WO disclosed
WO-2025003471-A1 COMBINATION THERAPY ZEALAND PHARMA A/S (DK) 2025-01-02 — — WO disclosed
WO-2024261076-A1 WEIGHT LOSS ZEALAND PHARMA A/S (DK) 2024-12-26 — — WO disclosed
WO-2024261259-A1 ANALOGUES WITH IMPROVED PROPERTIES ZEALAND PHARMA A/S (DK) 2024-12-26 — — WO disclosed
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