Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165454 | 0.80 | EPHX2 (0.43) | EPHX2KAT2BATMKMT2AALDH1A1 | |
| SCHEMBL1104785 | 0.77 | ALDH1A1 (0.44) | KAT2BMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8643448 | 0.76 | ESR1 (0.55) | KMT2AALDH1A1KDM4EESR1PDCD1 | |
| SCHEMBL28018148 | 0.75 | ALDH1A1 (0.48) | EPHX2KAT2BMEN1KMT2AALDH1A1 | |
| SCHEMBL9333908 | 0.74 | ALDH1A1 (0.41) | EPHX2KAT2BMEN1KMT2AALDH1A1 | |
| SCHEMBL31564825 | 0.74 | ALDH1A1 (0.41) | EPHX2KAT2BMEN1KMT2AALDH1A1 | |
| SCHEMBL3057963 | 0.74 | ALDH1A1 (0.41) | EPHX2KAT2BMEN1KMT2AALDH1A1 | |
| SCHEMBL169730 | 0.73 | TAAR1 (0.50) | KMT2AALDH1A1KDM4EESR1PDCD1 | |
| SCHEMBL7499823 | 0.73 | TAAR1 (0.50) | KMT2AALDH1A1KDM4EESR1PDCD1 | |
| Benzene SCHEMBL28192760 | 0.73 | TAAR1 (0.50) | KMT2AALDH1A1KDM4EESR1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093210-B2 | Treatment of sepsis with 5-ethyl-1-phenyl-2(1H)-pyridone | SOLANAN, INC. (US) | 2012-01-10 | — | — | US | disclosed |