SCHEMBL31295136

SCHEMBL31295136

CCOC(=O)C=Cc1cc(F)c(F)cc1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.55
FDPS P14324 1/20 0.52
NFE2L2 Q16236 1/20 0.49
DPP4 P27487 2/20 0.48
CYP3A4 P08684 1/20 0.47
AKR1B10 O60218 4/20 0.46
AKR1B1 P15121 4/20 0.46
ALOX5 P09917 1/20 0.46
TTR P02766 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
GABRA1 P14867 1/20 0.45
GABRB2 P47870 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17722573 0.91 MAOB (0.60) MAOBFDPSNFE2L2DPP4CYP3A4
SCHEMBL2352080 0.90 MAOB (0.53) MAOBFDPSDPP4CYP3A4AKR1B10
SCHEMBL2690713 0.85 FDPS (0.56) MAOBFDPSNFE2L2DPP4TTR
SCHEMBL5574666 0.85 FDPS (0.56) MAOBFDPSNFE2L2DPP4TTR
SCHEMBL17718560 0.85 MAOB (0.55) MAOBFDPSNFE2L2DPP4AKR1B10
SCHEMBL12035690 0.84 MAOB (0.51) MAOBFDPSDPP4CYP3A4AKR1B10
SCHEMBL757937 0.84 CYP3A4 (0.51) MAOBFDPSDPP4CYP3A4TTR
SCHEMBL757936 0.84 CYP3A4 (0.51) MAOBFDPSDPP4CYP3A4TTR
SCHEMBL31634682 0.82 MAOB (0.49) MAOBFDPSNFE2L2DPP4CYP3A4
SCHEMBL12035789 0.81 MAOB (0.48) MAOBFDPSDPP4CYP3A4AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119698412-A 5-HT2A receptor agonist, and preparation method and application thereof 上海翊石医药科技有限公司 2025-03-25 CN disclosed
WO-2025021120-A1 5-HT2A RECEPTOR AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翊石医药科技有限公司 2025-01-30 WO disclosed