Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395724 | 1.00 | MAPK8 (0.44) | MAPK8MAPK9IRAK4HTR2CADRB2 | |
| SCHEMBL31358121 | 0.91 | HTR2A (0.51) | MAPK8MAPK9IRAK4HTR2CKDM4E | |
| SCHEMBL7714021 | 0.91 | HTR2A (0.51) | MAPK8MAPK9IRAK4HTR2CKDM4E | |
| SCHEMBL29869220 | 0.90 | HTR2C (0.50) | MAPK8MAPK9IRAK4HTR2CADRB2 | |
| SCHEMBL1545976 | 0.90 | HTR2C (0.50) | MAPK8MAPK9IRAK4HTR2CADRB2 | |
| SCHEMBL3057752 | 0.83 | KDM4E (0.50) | HTR2CKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL15485748 | 0.80 | KDM4E (0.47) | HTR2CKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL4004747 | 0.80 | RAB9A (0.48) | HTR2CKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL8469607 | 0.76 | KDM4E (0.41) | MAPK8MAPK9IRAK4HTR2CKDM4E | |
| SCHEMBL31358034 | 0.76 | CHEK1 (0.47) | HTR2CHTR2AKCNH2HTR2BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119698412-A | 5-HT2A receptor agonist, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| WO-2025021120-A1 | 5-HT2A RECEPTOR AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2025-01-30 | — | — | WO | disclosed |