SCHEMBL31295331

SCHEMBL31295331

O=C(O)CCCN1CCC(c2c[nH]c3ccccc23)C1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.64
ADRA1D P25100 4/20 0.62
SLC6A4 P31645 1/20 0.60
HTR4 Q13639 2/20 0.59
KDM4E B2RXH2 1/20 0.58
ATM Q13315 1/20 0.58
CCR2 P41597 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31295165 0.93 CYP2D6 (0.67) CYP2D6ADRA1DSLC6A4KDM4EATM
SCHEMBL31295230 0.87 CYP2D6 (0.59) CYP2D6ADRA1DSLC6A4KDM4EATM
SCHEMBL31295190 0.87 CYP2D6 (0.59) CYP2D6ADRA1DSLC6A4KDM4EATM
SCHEMBL3380970 0.85 SLC6A4 (0.71) ADRA1DSLC6A4CCR2
SCHEMBL11786426 0.84 ADRA1D (0.66) ADRA1DSLC6A4CCR2
SCHEMBL31530770 0.83 CYP2D6 (0.55) CYP2D6ADRA1DSLC6A4KDM4EATM
SCHEMBL31295121 0.83 CYP2D6 (0.55) CYP2D6ADRA1DSLC6A4KDM4EATM
SCHEMBL31295260 0.83 CYP2D6 (0.60) CYP2D6ADRA1DSLC6A4KDM4EATM
Hydrochloric Acid SCHEMBL11784755 0.83 ADRA1D (0.67) ADRA1DSLC6A4CCR2
SCHEMBL27707244 0.82 KDM4E (0.64) CYP2D6ADRA1DSLC6A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025021120-A1 5-HT2A RECEPTOR AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翊石医药科技有限公司 2025-01-30 WO disclosed