⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42541 | 0.71 | — | — | |
| SCHEMBL38204 | 0.69 | — | — | |
| SCHEMBL38203 | 0.69 | — | — | |
| SCHEMBL2551469 | 0.65 | — | — | |
| SCHEMBL2551472 | 0.65 | — | — | |
| SCHEMBL4665719 | 0.64 | — | — | |
| SCHEMBL8769427 | 0.64 | — | — | |
| SCHEMBL4664231 | 0.62 | — | — | |
| SCHEMBL150022 | 0.60 | — | — | |
| SCHEMBL150021 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787788-B2 | Benzimidazole derivatives, and pharmaceutical compositions and methods of use thereof | CAPELLA THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230271938-A1 | BENZIMIDAZOLES FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES | CAPELLA THERAPEUTICS, INC. | 2023-08-31 | — | — | US | disclosed |
| US-11713322-B2 | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer | CAPELLA THERAPEUTICS, INC. (US) | 2023-08-01 | — | — | US | disclosed |
| US-20230233562-A1 | HETEROARYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC USE | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2023-07-27 | — | — | US | disclosed |
| EP-3362075-B1 | NATURAL KILLER CELLS AND ILC3 CELLS AND USES THEREOF | CELULARITY INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230142803-A1 | NATURAL KILLER CELLS AND ILC3 CELLS AND USES THEREOF | CELULARITY INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230136999-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING ONE OR MORE PYRONE COMPOUNDS, AND THEIR USE FOR TREATING INFLAMMATORY AND NEURODEGENERATIVE DISEASES | Neuro TheryX Canada LTD (CA) | 2023-05-04 | — | — | US | disclosed |
| US-20220323449-A1 | (ALPHA-SUBSTITUTED ARALKYLAMINO AND HETEROARYLALKYLAMINO) PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES | MEI PHARMA, INC. | 2022-10-13 | — | — | US | disclosed |
| CN-114989140-A | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer | 卡佩拉医疗公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114940673-A | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer | 卡佩拉医疗公司 | 2022-08-26 | — | — | CN | disclosed |
| US-20040063584-A1 | Benzazolonylcarbonylcyclohexenones and their use ss herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-01 | — | — | US | disclosed |
| US-20040033899-A1 | 5[(pyrazol-4-yl)carbonyl]benzazolone as herbicide | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-19 | — | — | US | disclosed |
| EP-1177194-B1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6589915-B1 | The invention relates to cyclohexenone derivatives of benzo-condensed, unsaturated 5-ring nitrogen heterocycles of general formula (I) wherein X represents N or a group C-R3, Y represents O, S, SO, SO2 or NR4 or X-Y represent S | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | disclosed |
| US-6541423-B1 | Controlling vegatation | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |
| US-6352959-B1 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-05 | — | — | US | disclosed |
| EP-0513580-B1 | Alpha-phenyl-acrylic acid derivatives, process for their preparation and their use as parasiticides and fungicides | BASF AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| US-5416068-A | Alpha-phenylacrylic acid derivatives, their preparation and their use for controlling pests and harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-16 | — | — | US | disclosed |
| US-5298527-A | Insecticides | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-29 | — | — | US | disclosed |
| EP-0513580-A2 | Alpha-phenyl-acrylic acid derivatives, process for their preparation and their use as parasiticides and fungicides | BASF Aktiengesellschaft (DE) | 1992-11-19 | — | — | EP | disclosed |