⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38204 | 1.00 | — | — | |
| SCHEMBL2551469 | 0.94 | — | — | |
| SCHEMBL2551472 | 0.94 | — | — | |
| SCHEMBL27531668 | 0.88 | TSHR (0.32) | — | |
| SCHEMBL29284464 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL4099962 | 0.82 | TRPV1 (0.39) | — | |
| SCHEMBL28730970 | 0.82 | ALDH1A1 (0.39) | — | |
| SCHEMBL4099959 | 0.82 | TRPV1 (0.39) | — | |
| SCHEMBL27713832 | 0.78 | — | — | |
| SCHEMBL29284344 | 0.78 | TRPV1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3513 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000070-B1 | SILICON-CONTAINING CHAIN EXTENDERS | AORTECH BIOMATERIALS PTY LTD (AU) | 2003-09-10 | — | — | EP | claimed |
| EP-0984997-B1 | SILICON-BASED POLYCARBONATES | AORTECH BIOMATERIALS PTY LTD (AU) | 2002-09-18 | — | — | EP | claimed |
| EP-0823254-B1 | NOVEL USE OF PYRAZOLOPYRIDINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-07-17 | — | — | EP | claimed |
| US-6420452-B1 | POLYURETHANES WITH EXTENDERS | AORTECH BIOMATERIALS PTY LTD (AU) | 2002-07-16 | — | — | US | claimed |
| JP-51118788-A | — | — | None | — | — | JP | disclosed |
| US-12042479-B2 | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders | INMED PHARMACEUTICALS INC. | 2024-07-23 | — | — | US | disclosed |
| US-20240239762-A1 | NOVEL HETEROCYCLIC COMPOUNDS | FLORATEK PHARMA S A (CH) | 2024-07-18 | — | — | US | disclosed |
| US-20240239751-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | BRIDGEBIO GENE THERAPY RESEARCH, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240238427-A1 | METHODS OF TREATING AN EYE DISORDER | KODIAK SCIENCES INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
| CN-118344348-A | Heterocyclic substituted quinazoline and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| US-4289778-A | SYSTEMIC INSECTICIDES | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0034249-A2 | New naphthimidazole and naphthoxazole derivatives, their preparation, and their use in pharmaceuticals | GRUPPO LEPETIT S.P.A. (IT) | 1981-08-26 | — | — | EP | disclosed |
| US-4195092-A | INSECTICIDES FOR TREATING MEXICAN BEAN BEETLE | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| EP-0003081-A2 | Thiazolidinecarbothioamides, their preparation, compositions and use as insecticides | ELI LILLY AND COMPANY (US) | 1979-07-25 | — | — | EP | disclosed |
| EP-0002939-A2 | Novel carbothioamides, compositions containing them and their preparation | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |
| EP-0002938-A2 | Novel heterocyclic carbothioamides, compositions containing them, their preparation and use | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |
| JP-S51118788-A | METHOD FOR SYNTHESIZING NOVEL PENICILLIN DERIVATIVES | YAMANOUCHI PHARMACEUT CO LTD | 1976-10-18 | — | — | JP | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |