Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 9/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3311657 | 0.81 | CYP2A13 (1.00) | CYP2A13ALDH1A1KDM4EHTTSIGMAR1 | |
| SCHEMBL11193326 | 0.79 | CYP2A13 (0.75) | CYP2A13LMNAALDH1A1KDM4EHTT | |
| SCHEMBL3730392 | 0.77 | CYP2A13 (0.67) | CYP2A13LMNAALDH1A1KDM4EHTT | |
| SCHEMBL4105461 | 0.75 | CYP2A13 (1.00) | CYP2A13ALDH1A1KDM4EHTTSIGMAR1 | |
| SCHEMBL3738488 | 0.75 | CYP2A13 (0.69) | CYP2A13LMNAALDH1A1KDM4EHTT | |
| SCHEMBL28827491 | 0.74 | CYP2A13 (0.63) | CYP2A13LMNAALDH1A1KDM4EHTT | |
| SCHEMBL11512000 | 0.74 | MAPT (0.62) | ALDH1A1KDM4EHTTSMN1; SMN2SIGMAR1 | |
| SCHEMBL18190383 | 0.73 | CYP2A13 (0.71) | CYP2A13ALDH1A1KDM4EHTTSIGMAR1 | |
| SCHEMBL10513466 | 0.72 | CYP2A13 (0.65) | CYP2A13LMNAALDH1A1KDM4EHTT | |
| SCHEMBL22957610 | 0.72 | CYP2A13 (0.59) | CYP2A13LMNAALDH1A1KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035221-A1 | PYRAZOLO PYRIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2010-04-01 | — | — | WO | disclosed |