Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | BHMT | Q93088 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130457 | 1.00 | GSR (0.53) | GSRDPP9DPP4GNAI3GNAO1 | |
| SCHEMBL6130458 | 1.00 | GSR (0.53) | GSRDPP9DPP4GNAI3GNAO1 | |
| SCHEMBL29245609 | 0.82 | GSR (0.52) | GSRDPP9DPP4GNAI3GNAO1 | |
| SCHEMBL11313518 | 0.81 | GSR (0.39) | GSRRNPEPCYP2D6NFKB1CPB2 | |
| SCHEMBL29750499 | 0.80 | DPP4 (0.67) | GSRDPP9DPP4DPP8BHMT | |
| SCHEMBL2280440 | 0.80 | GSR (0.57) | GSRDPP9DPP4GNAI3GNAO1 | |
| SCHEMBL29615246 | 0.79 | DPP4 (0.47) | DPP9DPP4NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL8078485 | 0.78 | GSR (0.55) | GSRDPP9DPP4GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL21931161 | 0.78 | GSR (0.55) | GSRDPP9DPP4GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL14311789 | 0.78 | GSR (0.55) | GSRDPP9DPP4GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12616739-B2 | GLP-1 prodrugs and uses thereof | NOVO NORDISK A/S (DK) | 2026-05-05 | — | — | US | disclosed |
| US-20250268986-A1 | GLP-1 PRODRUGS AND USES THEREOF | NOVO NORDISK A/S (DK) | 2025-08-28 | — | — | US | disclosed |
| CN-119236123-A | HSP 90-targeting conjugates and formulations thereof | 融合制药公司 | 2025-01-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250268986-A1 | GLP-1 PRODRUGS AND USES THEREOF | GLP1R, IAPP, GCG | GSR 3142/4885DPP9 17/4885DPP4 6/4885 |
| US-12616739-B2 | GLP-1 prodrugs and uses thereof | GLP1R, SLC5A1, IAPP | GSR 4728/4885DPP9 32/4885DPP4 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.