Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | BHMT | Q93088 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540216 | 0.85 | PTGS1 (0.46) | DPP4DPP9ENPEPANPEPBHMT | |
| SCHEMBL29540065 | 0.85 | PTGS1 (0.46) | DPP4DPP9ENPEPANPEPBHMT | |
| SCHEMBL29750499 | 0.83 | DPP4 (0.67) | DPP4DPP9ENPEPANPEPBHMT | |
| L-Homocysteine SCHEMBL8017313 | 0.79 | BHMT (0.50) | ENPEPANPEPBHMTPTGS1SLC7A11 | |
| Homocysteine SCHEMBL8017311 | 0.79 | BHMT (0.50) | ENPEPANPEPBHMTPTGS1SLC7A11 | |
| SCHEMBL6130458 | 0.79 | GSR (0.53) | DPP4DPP9BHMTNOS3NOS1 | |
| SCHEMBL31297464 | 0.79 | GSR (0.53) | DPP4DPP9BHMTNOS3NOS1 | |
| SCHEMBL6130457 | 0.79 | GSR (0.53) | DPP4DPP9BHMTNOS3NOS1 | |
| SCHEMBL30063665 | 0.79 | DPP4 (0.43) | DPP4DPP9BHMTNOS3NOS1 | |
| SCHEMBL29607520 | 0.76 | NOD1 (0.39) | DPP4DPP9PTGS1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260053885-A1 | PHARMACEUTICAL COMPOSITIONS | RHYTHM PHARMACEUTICALS INC (US) | 2026-02-26 | — | — | US | disclosed |
| US-12285460-B2 | Pharmaceutical compositions | RHYTHM PHARMACEUTICALS, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| US-20220160818-A1 | PHARMACEUTICAL COMPOSITIONS | RHYTHM PHARMACEUTICALS, INC. | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160818-A1 | PHARMACEUTICAL COMPOSITIONS | PCTP, SLC27A1, CETP | DPP4 2850/4885DPP9 2683/4885ENPEP 440/4885 |
| US-12285460-B2 | Pharmaceutical compositions | PCTP, SLC27A1, CETP | DPP4 2850/4885DPP9 2683/4885ENPEP 440/4885 |
| US-20260053885-A1 | PHARMACEUTICAL COMPOSITIONS | ARGLU1, FFAR3, ASNS | DPP4 1288/4885DPP9 791/4885ENPEP 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.