Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297651 | 0.81 | CYP17A1 (0.42) | SMN1; SMN2NPC1RAB9AMAPTGFER | |
| SCHEMBL31297581 | 0.81 | RAB9A (0.42) | SMN1; SMN2NPC1RAB9AMAPTGFER | |
| SCHEMBL31297657 | 0.76 | PRKCI (0.42) | TLR8TLR7NPC1RAB9AMAPT | |
| SCHEMBL20764962 | 0.70 | PDE4D (0.44) | SMN1; SMN2MEN1KMT2AHPGDTLR8 | |
| SCHEMBL31297547 | 0.68 | MAPT (0.45) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL28015323 | 0.68 | TLR8 (0.62) | SMN1; SMN2MEN1KMT2AHPGDTLR8 | |
| SCHEMBL13313436 | 0.67 | NQO2 (0.46) | SMN1; SMN2S1PR1ALDH1A1NPC1RAB9A | |
| SCHEMBL26259911 | 0.67 | TLR8 (0.66) | SMN1; SMN2MEN1KMT2AHPGDTLR8 | |
| SCHEMBL5988696 | 0.66 | HPGD (0.65) | SMN1; SMN2MEN1KMT2AHPGDTLR8 | |
| SCHEMBL31297552 | 0.65 | PRKCI (0.41) | SMN1; SMN2KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |