Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.32 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.32 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297716 | 0.82 | CCNC (0.44) | MAPK1CCNCCDK8FYNDYRK1A | |
| SCHEMBL31297646 | 0.80 | DYRK1A (0.51) | MAPK1CCNCCDK8FYNDYRK1A | |
| SCHEMBL31297623 | 0.78 | CCNC (0.47) | MAPK1CCNCCDK8FYNDYRK1A | |
| SCHEMBL31297678 | 0.77 | KIT (0.39) | MAPK1CCNCCDK8FYNDYRK1A | |
| SCHEMBL31297659 | 0.77 | MAPK1 (0.33) | MAPK1CCNCCDK8FYNDYRK1A | |
| SCHEMBL31297681 | 0.76 | GRM5 (0.33) | MAPK1CCNCCDK8FYNDYRK1A | |
| SCHEMBL31297666 | 0.75 | MAP3K7 (0.40) | MAPK1DYRK1ACLK1GABRA1GABRG2 | |
| SCHEMBL31297563 | 0.75 | MAPK13 (0.39) | MAPK1BRAFNPC1MAPTRAB9A | |
| SCHEMBL31297632 | 0.73 | SMN1; SMN2 (0.43) | MAPK1PTK2CYP19A1CYP1A2NPC1 | |
| SCHEMBL31297556 | 0.73 | NPC1 (0.33) | CYP19A1NPC1MAPTRAB9AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |