Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 5/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22346635 | 0.82 | GPR35 (0.31) | PRKCIGPR35 | |
| SCHEMBL29256710 | 0.81 | PDPK1 (0.34) | LMNAPRKCIGPR35KDM4E | |
| SCHEMBL19554995 | 0.80 | PRKCI (0.36) | LMNAPRKCIGPR35KDM4E | |
| SCHEMBL31297651 | 0.75 | CYP17A1 (0.42) | LMNAPRKCI | |
| SCHEMBL358314 | 0.73 | KDM4E (0.37) | LMNAPRKCIKDM4E | |
| SCHEMBL19554465 | 0.73 | KDM4E (0.43) | KDM4ENQO2 | |
| SCHEMBL29893450 | 0.72 | NPC1 (0.38) | LMNAPRKCIKDM4E | |
| SCHEMBL31570034 | 0.71 | PRKCI (0.33) | PRKCI | |
| SCHEMBL31745020 | 0.70 | PRKCI (0.32) | PRKCI | |
| SCHEMBL1284962 | 0.68 | GPR35 (0.32) | PRKCIGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |