Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3251375 | 0.86 | HTT (0.34) | — | |
| SCHEMBL3126792 | 0.76 | MAP4K4 (0.33) | — | |
| SCHEMBL567866 | 0.75 | — | — | |
| SCHEMBL3245961 | 0.74 | ALDH1A1 (0.37) | ALDH1A1LMNACAPN1PRMT1GLP1R | |
| SCHEMBL3245954 | 0.74 | ALDH1A1 (0.35) | ALDH1A1LMNACAPN1PRMT1GLP1R | |
| SCHEMBL3129819 | 0.73 | ALDH1A1 (0.34) | ALDH1A1LMNACAPN1 | |
| SCHEMBL3126594 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNACAPN1PRMT1 | |
| SCHEMBL3121506 | 0.66 | ALDH1A1 (0.46) | ALDH1A1LMNACAPN1PRMT1 | |
| SCHEMBL3123547 | 0.65 | ALDH1A1 (0.38) | ALDH1A1LMNACAPN1PRMT1 | |
| SCHEMBL9954937 | 0.64 | NR3C2 (0.38) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |