Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PTGFR | P43088 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835154 | 0.90 | MEN1 (0.67) | MEN1KMT2AHIF1AHSD11B1CYP2C19 | |
| SCHEMBL95518 | 0.89 | KMT2A (0.65) | MEN1KMT2AHIF1AHSD11B1KDM4E | |
| SCHEMBL16105732 | 0.89 | KMT2A (0.59) | MEN1KMT2AHIF1AHSD11B1KDM4E | |
| SCHEMBL16359225 | 0.89 | KMT2A (0.65) | MEN1KMT2AHIF1AHSD11B1KDM4E | |
| SCHEMBL3300374 | 0.89 | MEN1 (0.65) | MEN1KMT2AHIF1AHSD11B1SMN1; SMN2 | |
| SCHEMBL4703240 | 0.88 | MEN1 (0.58) | MEN1KMT2AHIF1AHSD11B1CYP1A2 | |
| SCHEMBL18773935 | 0.86 | KDM4E (0.64) | MEN1KMT2AHIF1AHSD11B1CYP2C19 | |
| SCHEMBL17886691 | 0.86 | MEN1 (0.66) | MEN1KMT2AHIF1AHSD11B1SMN1; SMN2 | |
| SCHEMBL2755865 | 0.86 | KDM4E (0.62) | MEN1KMT2AHIF1AHSD11B1CYP1A2 | |
| SCHEMBL11628586 | 0.85 | KMT2A (0.71) | MEN1KMT2AHIF1AHSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | MILLENNIUM PHARM INC (US) | 2025-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250043353-A1 | BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE | WNT1, XPOT, CTNNBL1 | MEN1 1646/4885KMT2A 598/4885HIF1A 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.