Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26255001 | 1.00 | HDAC1 (0.50) | HDAC1HDAC6FGFR1NAMPTPPARG | |
| Trifluoroacetic Acid SCHEMBL22533966 | 0.92 | HDAC1 (0.44) | HDAC1HDAC6FGFR1NAMPTPPARG | |
| SCHEMBL27442447 | 0.91 | HDAC1 (0.48) | HDAC1HDAC6FGFR1NAMPTPPARG | |
| SCHEMBL27441300 | 0.90 | HDAC1 (0.50) | HDAC1HDAC6CYP11B1CYP11B2HTT | |
| SCHEMBL22533960 | 0.89 | MEN1 (0.49) | HDAC1HDAC6FGFR1PPARGLMNA | |
| SCHEMBL22533916 | 0.85 | PPARG (0.52) | HDAC1HDAC6PPARGIDO1 | |
| SCHEMBL22533917 | 0.85 | BRD4 (0.52) | HDAC1HDAC6FGFR1PPARGCYP11B2 | |
| SCHEMBL22533968 | 0.84 | HDAC1 (0.43) | HDAC1HDAC6FGFR1NAMPTPPARG | |
| Trifluoroacetic Acid SCHEMBL22533911 | 0.83 | HDAC1 (0.44) | HDAC1HDAC6CYP11B1CYP11B2TNF | |
| Trifluoroacetic Acid SCHEMBL29424806 | 0.83 | HDAC1 (0.44) | HDAC1HDAC6CYP11B1CYP11B2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250041319-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC | 2025-02-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250041319-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | ENPP1, ENPP3, SMPD1 | HDAC1 661/4885HDAC6 982/4885FGFR1 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.