SCHEMBL31298652

CC(C)Cc1ccc(CCCC(=O)NCCCCC(NC(=O)C(CCCCNC(=O)OC(C)(C)C)NC(=O)CCOCCOCCOCCNC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	KLK7	P49862	2/20	0.45

▸	KLK5	Q9Y337	2/20	0.45

▸	PAX8	Q06710	1/20	0.45

▸	TDP1	Q9NUW8	1/20	0.45

▸	PSMB1	P20618	2/20	0.44

▸	PSMB5	P28074	2/20	0.44

▸	PSMB2	P49721	2/20	0.44

▸	MAPT	P10636	1/20	0.44

▸	SIRT2	Q8IXJ6	2/20	0.42

▸	MMP1	P03956	1/20	0.42

▸	MMP3	P08254	1/20	0.42

▸	MMP9	P14780	1/20	0.42

▸	CPB1	P15086	1/20	0.42

▸	CPB2	Q96IY4	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30783519	0.97	SIRT2 (0.46)	KLK7KLK5PAX8TDP1PSMB1
SCHEMBL30783484	0.96	KLK7 (0.47)	KLK7KLK5PAX8TDP1MAPT
SCHEMBL30783460	0.93	CPB1 (0.52)	KLK7KLK5SIRT2CPB1CPB2
SCHEMBL31298666	0.89	CA1 (0.44)	PAX8TDP1PSMB1PSMB5PSMB2
SCHEMBL30783505	0.89	SIRT2 (0.54)	KLK7KLK5MAPTSIRT2
SCHEMBL27261452	0.89	SIRT2 (0.54)	KLK7KLK5MAPTSIRT2
SCHEMBL31298682	0.88	PTPN1 (0.41)	PAX8TDP1PSMB1PSMB5PSMB2
SCHEMBL30783468	0.87	KLK7 (0.51)	KLK7KLK5PAX8TDP1MAPT
SCHEMBL30783496	0.87	KLK7 (0.51)	KLK7KLK5PAX8TDP1MAPT
SCHEMBL31298691	0.87	KLK7 (0.56)	KLK7KLK5PAX8TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025029608-A1	FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF	RATIO THERAPEUTICS, INC. (US)	2025-02-06	—	—	WO	disclosed