SCHEMBL31298676

SCHEMBL31298676

CC(C)Cc1ccc(CCCC(=O)NCCCCC(C)NC(=O)C(CCCCN)NC(=O)CCOCCOCCOCCNC(=O)OCC2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 2/20 0.44
▸ PTPN1 P18031 6/20 0.42
▸ KMT2A Q03164 1/20 0.41
▸ CALCRL Q16602 1/20 0.40
▸ CPB1 P15086 1/20 0.39
▸ CPB2 Q96IY4 1/20 0.39
▸ OPRK1 P41145 2/20 0.38
▸ GRB2 P62993 1/20 0.38
▸ CCKAR P32238 1/20 0.37
▸ CCKBR P32239 1/20 0.37
▸ PLG P00747 1/20 0.37
▸ PRSS1 P07477 1/20 0.37
▸ PRSS2 P07478 1/20 0.37
▸ PRSS3 P35030 1/20 0.37
▸ TPSAB1 Q15661 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31298701 0.94 CPB1 (0.45) TLR2PTPN1KMT2ACALCRLCPB1
SCHEMBL31298682 0.87 PTPN1 (0.41) TLR2PTPN1KMT2AGRB2
SCHEMBL31298671 0.85 ALB (0.48) TLR2KMT2ACALCRLCPB1CPB2
SCHEMBL32670193 0.84 PTPN1 (0.41) TLR2PTPN1GRB2TPSAB1
SCHEMBL20530026 0.81 ALB (0.53) TLR2KMT2A
SCHEMBL19541911 0.81 TLR2 (0.56) TLR2KMT2ACPB1CPB2TPSAB1
SCHEMBL22514287 0.81 TLR2 (0.54) TLR2KMT2ACPB1CPB2TPSAB1
SCHEMBL19542209 0.81 TLR2 (0.56) TLR2KMT2ACPB1CPB2TPSAB1
SCHEMBL30895420 0.80 KMT2A (0.52) TLR2KMT2A
SCHEMBL29521888 0.80 ALB (0.44) TLR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025029608-A1 FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF RATIO THERAPEUTICS, INC. (US) 2025-02-06 — — WO disclosed
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