Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828519 | 0.79 | MAPT (0.55) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL20620221 | 0.73 | CLK1 (0.61) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL15757369 | 0.70 | CDK5 (0.57) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL7503298 | 0.70 | NR4A2 (0.62) | MAPTSMN1; SMN2ALDH1A1HSD17B10PDGFRB | |
| SCHEMBL4398433 | 0.70 | MAPT (0.62) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL31298718 | 0.70 | CYP1A2 (0.54) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL28507270 | 0.70 | ASH1L (0.55) | SMN1; SMN2HSD17B10TUBB4ATUBBTUBA3C | |
| SCHEMBL7496465 | 0.69 | DYRK1A (0.63) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL25034150 | 0.69 | TUBB4A (0.68) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL31298753 | 0.69 | MEN1 (0.59) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024218798-A1 | AMINOPYRIDINE ANALOGUES AS 5-HYDROXYTRYPTAMINE RECEPTOR MODULATORS AND USES THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2024-10-24 | — | — | WO | claimed |
| WO-2024218798-A1 | AMINOPYRIDINE ANALOGUES AS 5-HYDROXYTRYPTAMINE RECEPTOR MODULATORS AND USES THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2024-10-24 | — | — | WO | disclosed |