SCHEMBL31299705

SCHEMBL31299705

CCCCCCCCN(CCCCCCCC)S(=O)(=O)CCCCCCCCl

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
CNR2 P34972 1/20 0.46
FAAH O00519 3/20 0.41
CA2 P00918 3/20 0.37
THRB P10828 4/20 0.37
THRA P10827 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
DNM1 Q05193 1/20 0.35
CES1 P23141 2/20 0.35
CES2 O00748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31299683 1.00 TSHR (0.48) TSHRALDH1A1CNR2FAAHCA2
SCHEMBL31299720 1.00 TSHR (0.48) TSHRALDH1A1CNR2FAAHCA2
SCHEMBL31299677 1.00 TSHR (0.48) TSHRALDH1A1CNR2FAAHCA2
SCHEMBL31299689 0.98 TSHR (0.46) TSHRALDH1A1CNR2FAAHCA2
SCHEMBL7098991 0.94 TSHR (0.44) TSHRALDH1A1CNR2FAAHCA2
SCHEMBL7105033 0.94 TSHR (0.44) TSHRALDH1A1CNR2FAAHCA2
SCHEMBL7856362 0.90 CNR2 (0.51) CNR2FAAHCA2THRBTHRA
SCHEMBL9526928 0.90 CNR2 (0.51) CNR2FAAHCA2THRBTHRA
SCHEMBL31722142 0.90 CNR2 (0.51) CNR2FAAHCA2THRBTHRA
SCHEMBL7097527 0.89 CA1 (0.43) TSHRALDH1A1CNR2FAAHCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731606-A1 IONIZABLE THIOLIPIDS AND USES THEREOF BioNTech SE (DE) 2026-04-29 EP disclosed
WO-2025027089-A1 IONIZABLE THIOLIPIDS AND USES THEREOF BioNTech SE (DE) 2025-02-06 WO disclosed