Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098991 | 1.00 | TSHR (0.44) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299689 | 0.96 | TSHR (0.46) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299683 | 0.94 | TSHR (0.48) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299705 | 0.94 | TSHR (0.48) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299720 | 0.94 | TSHR (0.48) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299677 | 0.94 | TSHR (0.48) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL14229093 | 0.92 | TSHR (0.40) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL7097400 | 0.90 | CA1 (0.43) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL7097527 | 0.90 | CA1 (0.43) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL14230183 | 0.89 | CA1 (0.41) | TSHRALDH1A1CNR2TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |