SCHEMBL31300136

SCHEMBL31300136

O=C1NCCC1Cc1ccc(/C=C/Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.37
CRBN Q96SW2 1/20 0.37
HTT P42858 1/20 0.35
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
MAOB P27338 2/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6211599 0.80 MAOB (0.46) DDB1CRBNHTTMAOB
SCHEMBL3051430 0.76 ALDH1A1 (0.44) DDB1CRBNHTTGAAPOLB
SCHEMBL31300144 0.76 DDB1 (0.41) DDB1CRBNHTTGAAPOLB
SCHEMBL28260107 0.76 KMT2A (0.43) DDB1CRBNHTTGAAPOLB
SCHEMBL1963328 0.76 CRBN (0.41) DDB1CRBNHTTGAAPOLB
SCHEMBL837901 0.76 DDB1 (0.60) DDB1CRBNPOLBKMT2AMAOB
SCHEMBL7126821 0.73 PSEN1 (0.45)
SCHEMBL28261454 0.73 DDB1 (0.39) DDB1CRBNHTTGAAPOLB
SCHEMBL28103924 0.73 PSEN1 (0.43) DDB1CRBNHTT
SCHEMBL28206454 0.73 HTT (0.48) CRBNHTTGAAPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737448-A1 SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF Artivila (ShenZhen) Innovation Center, Ltd. (CN) 2026-05-06 EP disclosed
WO-2025002030-A1 SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF 科辉智药(深圳)新药研究中心有限公司 2025-01-02 WO disclosed