SCHEMBL31300348

SCHEMBL31300348

Fc1cc(F)cc(NC2CCc3ccccc32)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 1/20 0.60
PDPK1 O15530 1/20 0.53
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
KMT2A Q03164 2/20 0.46
MAOA P21397 3/20 0.45
MAOB P27338 3/20 0.45
BCHE P06276 1/20 0.45
ADRA2B P18089 1/20 0.45
ADRA2C P18825 1/20 0.45
ACHE P22303 1/20 0.45
ADRA1A P35348 1/20 0.45
HTR6 P50406 1/20 0.45
NSD2 O96028 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4741360 0.88 FADS1 (0.69) FADS1PDPK1CA1CA2KMT2A
SCHEMBL9541314 0.81 FADS1 (0.69) FADS1PDPK1CA1CA2KMT2A
SCHEMBL31300377 0.81 FADS1 (0.69) FADS1PDPK1CA1CA2KMT2A
SCHEMBL31300350 0.78 FADS1 (0.54) FADS1PDPK1CA1CA2KMT2A
SCHEMBL31300325 0.78 FADS1 (0.64) FADS1PDPK1CA1CA2KMT2A
SCHEMBL4935777 0.75 FADS1 (1.00) FADS1PDPK1CA1CA2KMT2A
SCHEMBL15137259 0.75 EGFR (0.54) FADS1PDPK1KMT2AMAOAMAOB
SCHEMBL2322457 0.73 PDPK1 (0.70) FADS1PDPK1CA1CA2MAOA
SCHEMBL28109682 0.72 PDPK1 (0.54) FADS1PDPK1CA1CA2KMT2A
SCHEMBL12047881 0.72 FADS1 (0.57) FADS1PDPK1CA1CA2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107556366-B Compound having mutant isocitrate dehydrogenase inhibitory activity, process for producing the same, and use thereof 上海海和药物研究开发股份有限公司 2025-02-07 CN disclosed