Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 1.00 |
| ▸ | MEN1 | O00255 | 12/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | GAA | P10253 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 0.75 |
| ▸ | THRB | P10828 | 4/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | CASP6 | P55212 | 1/20 | 0.65 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | RRM1 | P23921 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029030 | 1.00 | KMT2A (1.00) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL2029031 | 1.00 | KMT2A (1.00) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL29785654 | 1.00 | KMT2A (1.00) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL16323254 | 0.98 | KMT2A (0.97) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL23761140 | 0.93 | KMT2A (0.87) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL28039588 | 0.90 | KMT2A (0.82) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL9179463 | 0.86 | KMT2A (0.75) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL9179465 | 0.86 | KMT2A (0.75) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL11895330 | 0.86 | KMT2A (0.75) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL10049041 | 0.85 | KMT2A (0.74) | KMT2AMEN1MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240417806-A1 | METHODS OF IDENTIFYING AND TREATING CANCERS UTILIZING ALTERNATIVE LENGTHENING OF TELOMERE PATHWAY (ALT+ CANCERS) | NEW YORK INSTITUTE OF TECHNOLOGY | 2024-12-19 | — | — | US | claimed |
| WO-2025088175-A1 | ALC1 INHIBITORS FOR USE IN TREATING CANCER BY POTENTIATING THE EFFECTS OF SEVERAL CLASSES OF APPROVED CANCER DRUGS | EISBACH BIO GMBH (DE) | 2025-05-01 | — | — | WO | disclosed |
| US-20240417806-A1 | METHODS OF IDENTIFYING AND TREATING CANCERS UTILIZING ALTERNATIVE LENGTHENING OF TELOMERE PATHWAY (ALT+ CANCERS) | NEW YORK INSTITUTE OF TECHNOLOGY | 2024-12-19 | — | — | US | disclosed |