Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.75 |
| ▸ | MEN1 | O00255 | 11/20 | 0.75 |
| ▸ | GAA | P10253 | 7/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179463 | 1.00 | KMT2A (0.75) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL23761140 | 0.89 | KMT2A (0.87) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL29785654 | 0.86 | KMT2A (1.00) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL2029030 | 0.86 | KMT2A (1.00) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL2029031 | 0.86 | KMT2A (1.00) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL28039588 | 0.86 | KMT2A (0.82) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL31301126 | 0.86 | KMT2A (1.00) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL16323254 | 0.84 | KMT2A (0.97) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL11895330 | 0.82 | KMT2A (0.75) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL10049041 | 0.81 | KMT2A (0.74) | KMT2AMEN1GAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426085-A | Used in pressure sensitive carbonless copoly-papers; image formed by reaction of color forming compound and transition metal compound | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-06-20 | — | — | US | disclosed |
| US-5376451-A | Aromatic substituted compounds capable of forming coordination compounds with transition metal salts; used in pressure sensitive carbonless copy-papers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-27 | — | — | US | disclosed |