Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548190 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2NQO2MTNR1AMTNR1BGAA | |
| SCHEMBL547259 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TRPV1CA1CA2 | |
| SCHEMBL31409460 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TRPV1CA1CA2 | |
| SCHEMBL547261 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TRPV1CA1CA2 | |
| SCHEMBL547260 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TRPV1CA1CA2 | |
| SCHEMBL15188762 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2NQO2MTNR1AMTNR1B | |
| SCHEMBL15188760 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2NQO2MTNR1AMTNR1B | |
| SCHEMBL15188761 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2NQO2MTNR1AMTNR1B | |
| SCHEMBL548183 | 0.83 | — | — | |
| SCHEMBL548185 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734977-A2 | NOVEL TRPV1 AGONISTS AND USES THEREOF | Neucures, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006675-A9 | NOVEL TRPV1 AGONISTS AND USES THEREOF | NEUCURES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| WO-2025006675-A2 | NOVEL TRPV1 AGONISTS AND USES THEREOF | NEUCURES, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| EP-2566850-B1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE HYDROBROMIDE SALT | RICHTER GEDEON NYRT (HU) | 2018-04-11 | — | — | EP | disclosed |
| US-9506095-B2 | Process for the enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid or esters thereof, and application in the synthesis of ivabradine and salts thereof | LES LABORATORIES SERVIER (FR) | 2016-11-29 | — | — | US | disclosed |
| US-20130210091-A1 | PROCESS FOR THE ENZYMATIC SYNTHESIS OF (7S)-3,4-DIMETHOXYBICYCLO[4.2.0]OCTA-1,3,5-TRIENE-7-CARBOXYLIC ACID OR ESTERS THEREOF, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND SALTS THEREOF | LES LABORATOIRES SERVIER (FR) | 2013-08-15 | — | — | US | disclosed |
| EP-2145871-A1 | New method for preparing functionalised benzocyclobutenes and its application to the synthesis of ivabradine and its addition salts with a pharmaceutically acceptable acid. | Les Laboratoires Servier (FR) | 2010-01-20 | — | — | EP | disclosed |