Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130145 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2NQO2MTNR1AMTNR1BGAA | |
| SCHEMBL547259 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TRPV1CA1CA2 | |
| SCHEMBL31409460 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TRPV1CA1CA2 | |
| SCHEMBL547261 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TRPV1CA1CA2 | |
| SCHEMBL547260 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TRPV1CA1CA2 | |
| SCHEMBL15188762 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2NQO2MTNR1AMTNR1B | |
| SCHEMBL15188760 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2NQO2MTNR1AMTNR1B | |
| SCHEMBL15188761 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2NQO2MTNR1AMTNR1B | |
| SCHEMBL548183 | 0.83 | — | — | |
| SCHEMBL548185 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110701-B2 | Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | LES LABORATOIRES SERVIER (FR) | 2012-02-07 | — | — | US | disclosed |