Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31303093 | 0.84 | MAPT (0.67) | MAPTKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL25295618 | 0.84 | MAPT (0.67) | MAPTKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL25259360 | 0.80 | MAPT (0.50) | MAPTKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL31303089 | 0.79 | OGA (0.42) | POLBALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL24485872 | 0.75 | HTR3E (0.51) | MAPTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL3539499 | 0.74 | ACACB (0.43) | MAPTKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL25251729 | 0.74 | MAPT (0.41) | MAPTKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL31303095 | 0.74 | MAPT (0.41) | MAPTKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL25255513 | 0.72 | MAPT (0.46) | MAPTKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL31303103 | 0.72 | MAPT (0.46) | MAPTKMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013265-A | GLUT9 heterocyclic inhibitors for the treatment of disease | 爱尔兰好利恩治疗有限公司 | 2024-11-22 | — | — | CN | disclosed |