Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25224592 | 0.91 | MAPT (0.50) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL1392727 | 0.86 | MAPT (0.68) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL29435691 | 0.86 | MAPT (0.68) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL19021795 | 0.85 | MAPT (0.56) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL31006175 | 0.85 | MAPT (0.56) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL26641270 | 0.85 | MAPT (0.70) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL31303431 | 0.85 | MAPT (0.45) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL31303366 | 0.85 | GPR119 (0.46) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 | |
| SCHEMBL23114481 | 0.83 | MAPT (0.53) | MAPTLMNASMN1; SMN2POLBMET | |
| SCHEMBL25204395 | 0.83 | MAPT (0.56) | MAPTALDH1A1LMNAGPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024229393-A1 | HPK1 DEGRADERS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2024-11-07 | — | — | WO | disclosed |