Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128145 | 0.89 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3125211 | 0.85 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3131662 | 0.84 | MAPT (0.62) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3131560 | 0.83 | MAPT (0.61) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3127773 | 0.83 | MAPT (0.61) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL4493313 | 0.82 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3910984 | 0.82 | MAPT (0.60) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3910988 | 0.82 | MAPT (0.60) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3124699 | 0.82 | ALDH1A1 (0.77) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3134218 | 0.82 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021333-B1 | ANTI-PROLIFERATIVE COMPOUNDS DERIVING FROM A 3-ARYL-COUMARINE OR 3-ARYL-QUINOLIN-2-ONE AND USES THEREOF | EOS ETHICAL ONCOLOGY SCIENCE S (IT) | 2010-07-14 | — | — | EP | claimed |