Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.63 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.63 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | TNF | P01375 | 1/20 | 0.63 |
| ▸ | IL1B | P01584 | 1/20 | 0.63 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.63 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.47 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25011503 | 0.87 | CRBN (0.53) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25010559 | 0.87 | CRBN (0.53) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25010650 | 0.87 | CRBN (0.53) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25010555 | 0.87 | CRBN (0.53) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25011603 | 0.86 | CRBN (0.52) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL26103269 | 0.86 | CRBN (0.59) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL30304187 | 0.86 | CRBN (0.69) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25010105 | 0.85 | CRBN (0.51) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25012118 | 0.85 | CRBN (0.51) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL25011557 | 0.84 | CRBN (0.50) | CRBNIKZF3IKZF1BRD4TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024238872-A2 | ISOINDOLINONE-GLUTARIMIDE ANTIBODY CONJUGATES, AND USES THEREOF | FIREFLY BIO, INC. (US) | 2024-11-21 | — | — | WO | disclosed |