Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.69 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | IL1B | P01584 | 1/20 | 0.59 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305072 | 0.86 | CRBN (0.63) | CRBNIKZF3BRD4TNFIL1B | |
| SCHEMBL26103269 | 0.85 | CRBN (0.59) | CRBNIKZF3BRD4TNFIL1B | |
| SCHEMBL31443922 | 0.83 | CRBN (0.60) | CRBNIKZF3BRD4TNFIL1B | |
| SCHEMBL17724152 | 0.82 | CRBN (0.67) | CRBNIKZF3BRD4TNFIL1B | |
| SCHEMBL17724079 | 0.82 | CRBN (0.67) | CRBNIKZF3BRD4TNFIL1B | |
| SCHEMBL17724153 | 0.82 | CRBN (0.67) | CRBNIKZF3BRD4TNFIL1B | |
| SCHEMBL31443676 | 0.82 | CRBN (1.00) | CRBN | |
| SCHEMBL31444247 | 0.82 | CRBN (1.00) | CRBN | |
| SCHEMBL30304165 | 0.80 | CRBN (0.67) | CRBNIKZF3BRD4TNFIL1B | |
| SCHEMBL26105259 | 0.80 | CRBN (0.67) | CRBNIKZF3BRD4TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023056443-A1 | BINDERS OF CEREBLON AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-04-06 | — | — | WO | disclosed |