SCHEMBL31305643

SCHEMBL31305643

O=CN1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 2/20 1.00
HRH1 P35367 12/20 0.71
FNTA P49354 5/20 0.71
FNTB P49356 5/20 0.71
SLC6A15 Q9H2J7 5/20 0.71
MEN1 O00255 1/20 0.67
LMNA P02545 1/20 0.67
ADRB2 P07550 1/20 0.67
CHRM2 P08172 1/20 0.67
CHRM4 P08173 1/20 0.67
ABCB1 P08183 1/20 0.67
HTR1A P08908 1/20 0.67
CHRM5 P08912 1/20 0.67
ADRA2A P08913 1/20 0.67
CHRM1 P11229 1/20 0.67
DRD2 P14416 1/20 0.67
ADRA2B P18089 1/20 0.67
ADRA2C P18825 1/20 0.67
CHRM3 P20309 1/20 0.67
DRD1 P21728 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8876967 1.00 PTAFR (1.00) PTAFRHRH1FNTAFNTBSLC6A15
SCHEMBL4460572 0.87 HRH1 (0.82) PTAFRHRH1FNTAFNTBSLC6A15
SCHEMBL31384618 0.87 HRH1 (0.82) PTAFRHRH1FNTAFNTBSLC6A15
SCHEMBL29626502 0.87 HRH1 (0.82) PTAFRHRH1FNTAFNTBSLC6A15
SCHEMBL20777155 0.86 PTAFR (0.75) PTAFRHRH1FNTAFNTBSLC6A15
SCHEMBL8958672 0.86 PTAFR (0.75) PTAFRHRH1FNTAFNTBSLC6A15
SCHEMBL31414621 0.85 PTAFR (0.74) PTAFRHRH1FNTAFNTBSLC6A15
SCHEMBL3367280 0.84 SLC6A15 (0.82) PTAFRHRH1FNTAFNTBSLC6A15
SCHEMBL23303105 0.83 FNTA (1.00) PTAFRHRH1FNTAFNTBSLC6A15
Sch-37370 SCHEMBL3071641 0.83 PTAFR (1.00) PTAFRHRH1FNTAFNTBSLC6A15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119780305-A Method for analyzing and detecting related substances of desloratadine 浙江东亚药业股份有限公司 2025-04-08 CN disclosed
JP-2024180244-A DESLORATADINE SOLID PREPARATION 高田製薬株式会社 2024-12-26 JP disclosed