Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | CIT | O14578 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306355 | 0.85 | TRPV1 (0.58) | TRPV1TAAR1CITLTA4HNPC1 | |
| SCHEMBL31306287 | 0.78 | TRPV1 (0.61) | TRPV1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL18573111 | 0.78 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL31306169 | 0.78 | JAK2 (0.55) | TRPV1KDM4E | |
| SCHEMBL15244875 | 0.77 | TAAR1 (0.86) | TAAR1CITLTA4HXIAPSMN1; SMN2 | |
| SCHEMBL21480923 | 0.76 | TRPV1 (0.61) | TRPV1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL1751436 | 0.75 | TAAR1 (1.00) | TAAR1CITLTA4HXIAPNPC1 | |
| SCHEMBL4652086 | 0.75 | TAAR1 (1.00) | TAAR1CITLTA4HXIAPNPC1 | |
| Hydrochloric Acid SCHEMBL27930494 | 0.74 | TAAR1 (0.56) | TAAR1CITLTA4HXIAPKDM4E | |
| Hydrochloric Acid SCHEMBL16498368 | 0.74 | AAK1 (0.69) | TAAR1CITLTA4HXIAPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734979-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006723-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2025-01-02 | — | — | WO | disclosed |