Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86240 | 0.85 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL18573092 | 0.78 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL31306205 | 0.78 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL21480923 | 0.78 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL31306287 | 0.78 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL3872091 | 0.76 | TRPV1 (0.78) | TRPV1 | |
| SCHEMBL15779636 | 0.76 | TRPV1 (0.78) | TRPV1 | |
| SCHEMBL3878766 | 0.76 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL3554044 | 0.75 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL18573106 | 0.75 | TRPV1 (0.49) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11031562-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-08 | — | — | US | disclosed |
| WO-2017032439-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11031562-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | TRPV1 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.