Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488413 | 0.81 | SLC13A5 (0.46) | SLC13A5SMN1; SMN2ALKCCNKCDK12 | |
| SCHEMBL17066883 | 0.81 | ALK (0.50) | SLC13A5SMN1; SMN2LMNAALKCCNK | |
| SCHEMBL6070118 | 0.78 | SLC13A5 (0.50) | SLC13A5ALKABL1ALDH1A1HPGD | |
| SCHEMBL14405048 | 0.77 | SLC13A5 (0.46) | SLC13A5LMNAALKCCNKCDK12 | |
| SCHEMBL25412192 | 0.76 | SLC13A5 (0.43) | SLC13A5ALKCCNKCDK12ABL1 | |
| SCHEMBL25412190 | 0.76 | SLC13A5 (0.43) | SLC13A5ALKCCNKCDK12ABL1 | |
| SCHEMBL26963203 | 0.75 | SLC13A5 (0.44) | SLC13A5SMN1; SMN2ALKCCNKCDK12 | |
| Hydrochloric Acid SCHEMBL30416536 | 0.75 | SLC13A5 (0.42) | SLC13A5ALKCCNKCDK12ABL1 | |
| SCHEMBL16826278 | 0.75 | CYP3A4 (0.53) | SLC13A5SMN1; SMN2LMNACYP3A4CYP19A1 | |
| SCHEMBL12681327 | 0.71 | CCNK (0.39) | SLC13A5ALKCCNKCDK12ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734979-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006723-A2 | TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2025-01-02 | — | — | WO | disclosed |