Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFN | P31947 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | YWHAB | P31946 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306446 | 0.87 | ESR1 (0.54) | SFNESR1YWHABPDK1HPGD | |
| SCHEMBL31306473 | 0.86 | ESR1 (0.53) | SFNESR1YWHABPDK1HPGD | |
| SCHEMBL31306475 | 0.84 | ESR1 (0.56) | SFNESR1YWHABPDK1HPGD | |
| SCHEMBL31306499 | 0.84 | PTK2B (0.60) | SFNESR1YWHABPDK1RAB9A | |
| SCHEMBL31306463 | 0.82 | ESR1 (0.51) | SFNESR1YWHABPDK1HPGD | |
| SCHEMBL31306496 | 0.81 | ESR1 (0.58) | SFNESR1YWHABPDK1HPGD | |
| SCHEMBL31306441 | 0.81 | ESR1 (0.53) | SFNESR1YWHABPDK1HPGD | |
| SCHEMBL31306419 | 0.81 | ESR1 (0.54) | SFNESR1YWHABPDK1HPGD | |
| SCHEMBL31306465 | 0.80 | ESR1 (0.56) | SFNESR1YWHABPDK1RAB9A | |
| SCHEMBL31306483 | 0.80 | ESR1 (0.56) | SFNESR1YWHABPDK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731634-A1 | SMALL-MOLECULE STABILIZERS OF THE CHREBP 14-3-3 INTERACTION | Technische Universiteit Eindhoven (NL) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025005795-A1 | SMALL-MOLECULE STABILIZERS OF THE CHREBP 14-3-3 INTERACTION | TECHNISCHE UNIVERSITEIT EINDHOVEN (NL) | 2025-01-02 | — | — | WO | disclosed |