Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.45 |
| ▸ | PLK4 | O00444 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 5/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306505 | 0.96 | CRBN (0.53) | CRBNDDB1PLK4ARBTK | |
| SCHEMBL31306519 | 0.96 | CRBN (0.51) | CRBNDDB1PLK4ARBTK | |
| SCHEMBL31306474 | 0.92 | CRBN (0.49) | CRBNDDB1PLK4ARBTK | |
| SCHEMBL31306502 | 0.92 | CRBN (0.47) | CRBNDDB1PLK4ARBTK | |
| SCHEMBL31306506 | 0.90 | CRBN (0.55) | CRBNDDB1PLK4ARBTK | |
| SCHEMBL31306495 | 0.90 | CRBN (0.50) | CRBNDDB1ARALKIKZF3 | |
| SCHEMBL31306493 | 0.90 | CRBN (0.54) | CRBNDDB1ARIKZF3TNF | |
| SCHEMBL31306527 | 0.89 | CRBN (0.53) | CRBNDDB1ARIKZF3TNF | |
| SCHEMBL31306538 | 0.88 | CRBN (0.58) | CRBNDDB1PLK4ARBTK | |
| SCHEMBL31306515 | 0.87 | CRBN (0.57) | CRBNDDB1PLK4ARBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019370-A | Degradation agent targeting SIRT6 and/or GSPT1 and application thereof | 深圳大学 | 2024-11-26 | — | — | CN | disclosed |