Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 6/20 | 0.41 |
| ▸ | PLK4 | O00444 | 3/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306474 | 0.95 | CRBN (0.49) | CRBNDDB1IRAK1IRAK4IRAK3 | |
| SCHEMBL31306505 | 0.93 | CRBN (0.53) | CRBNDDB1IRAK1IRAK4IRAK3 | |
| SCHEMBL31306519 | 0.93 | CRBN (0.51) | CRBNDDB1ARPLK4BTK | |
| SCHEMBL31306481 | 0.92 | CRBN (0.50) | CRBNDDB1ARPLK4BTK | |
| SCHEMBL31306478 | 0.91 | CRBN (0.52) | CRBNDDB1IRAK1IRAK4IRAK3 | |
| SCHEMBL31306495 | 0.89 | CRBN (0.50) | CRBNDDB1ARALK | |
| SCHEMBL31306468 | 0.87 | CRBN (0.48) | CRBNDDB1IRAK1IRAK4IRAK3 | |
| SCHEMBL31306480 | 0.87 | CRBN (0.53) | CRBNDDB1IRAK1IRAK4IRAK3 | |
| SCHEMBL31306493 | 0.86 | CRBN (0.54) | CRBNDDB1IRAK1IRAK4IRAK3 | |
| SCHEMBL31306538 | 0.86 | CRBN (0.58) | CRBNDDB1IRAK1IRAK4IRAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019370-A | Degradation agent targeting SIRT6 and/or GSPT1 and application thereof | 深圳大学 | 2024-11-26 | — | — | CN | disclosed |