Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988135 | 1.00 | GSK3B (0.51) | GSK3BNTRK1PIK3CAHTTKDM4E | |
| Hydrochloric Acid SCHEMBL21988060 | 0.98 | GSK3B (0.50) | GSK3BNTRK1PIK3CAHTTKDM4E | |
| Hydrochloric Acid SCHEMBL30279704 | 0.98 | GSK3B (0.50) | GSK3BNTRK1PIK3CAHTTKDM4E | |
| SCHEMBL20846081 | 0.79 | MET (0.41) | NTRK1PIK3CANEK1AAK1CYP2C9 | |
| SCHEMBL29881388 | 0.79 | BTK (0.40) | NTRK1PIK3CANEK1AAK1CYP2C9 | |
| SCHEMBL17787159 | 0.79 | BTK (0.40) | NTRK1PIK3CANEK1AAK1CYP2C9 | |
| SCHEMBL1043610 | 0.79 | BRD4 (0.43) | NTRK1PIK3CAHTTKDM4EALDH1A1 | |
| SCHEMBL7867182 | 0.76 | KMT2A (0.47) | GSK3BNTRK1PIK3CANEK1AAK1 | |
| SCHEMBL7214036 | 0.74 | HTT (0.49) | NTRK1PIK3CAHTTKDM4EALDH1A1 | |
| SCHEMBL22050731 | 0.73 | JAK2 (0.41) | NTRK1PIK3CANEK1AAK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004785-A | Compounds and compositions for the treatment of diseases associated with STING activity | 诺华制药股份有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-112823036-B | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-11-08 | — | — | CN | disclosed |