Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307607 | 1.00 | MME (0.46) | MMEALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL23058790 | 0.89 | MME (0.41) | MMEALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL23055167 | 0.89 | MME (0.41) | MMEALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL27182865 | 0.86 | MME (0.45) | MMEALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL16668245 | 0.86 | MME (0.53) | MMEBIRC2 | |
| SCHEMBL31307586 | 0.85 | MME (0.50) | MMEALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL371120 | 0.85 | MME (0.50) | MMEALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL8475947 | 0.85 | MME (0.50) | MMEALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL31754261 | 0.83 | DPP7 (0.53) | BIRC2 | |
| SCHEMBL17465619 | 0.82 | CYP2C9 (0.53) | ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301105-A | Thiostrepton-based compounds for the treatment of cancer and preparation thereof | RS肿瘤学有限责任公司 | 2025-01-10 | — | — | CN | disclosed |