Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475947 | 1.00 | MME (0.50) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL31307586 | 1.00 | MME (0.50) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL22209522 | 0.85 | MME (0.47) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL4560808 | 0.85 | CAD (0.44) | MMEPAX8DPP4DPP8DPP7 | |
| SCHEMBL18620679 | 0.85 | MME (0.47) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL31307643 | 0.85 | MME (0.46) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL31307607 | 0.85 | MME (0.46) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL13380097 | 0.84 | MME (0.53) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL7327700 | 0.84 | MME (0.53) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| Hydrochloric Acid SCHEMBL38651024 | 0.84 | MME (0.46) | MMECYP2C9ALDH1A1THRBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254900-B1 | CHEMICAL MODIFICATION OF PROTEINS | ISIS INNOVATION (GB) | 2012-03-14 | — | — | EP | disclosed |