SCHEMBL3130869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3125030	0.85	MDM2 (0.46)	NPC1PDE10AL3MBTL1ATMCYP1A2
	SCHEMBL3128182	0.81	PDE10A (0.52)	PDE10AL3MBTL1ATMCYP1A2CYP2A6
	SCHEMBL3119753	0.79	PDE10A (0.48)	PDE10AL3MBTL1ATMCYP1A2CYP2A6
	SCHEMBL14997327	0.76	PDE10A (0.45)	NPC1PDE10AL3MBTL1ATMCYP1A2
	SCHEMBL3121339	0.74	HTR2B (0.50)	PDE10AL3MBTL1ATMCYP1A2CYP2A6
	SCHEMBL3823640	0.74	ATM (0.51)	NPC1PDE10AL3MBTL1ATMCYP1A2
	SCHEMBL3121450	0.73	HTR2C (0.42)	NPC1PDE10AL3MBTL1ATMHTR2C
	SCHEMBL17664090	0.73	NPC1 (0.40)	NPC1PDE10AL3MBTL1ATMCYP1A2
	SCHEMBL17664092	0.72	HSP90AB1 (0.47)	PDE10AL3MBTL1ATMCYP1A2CYP2A6
	SCHEMBL20097380	0.72	TAAR1 (0.46)	NPC1L3MBTL1HTR2CHTR2BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.