Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181352 | 0.95 | SCN9A (0.46) | SCN9APDE5ACYP3A4ALOX5APFEN1 | |
| SCHEMBL27354580 | 0.95 | SCN9A (0.46) | SCN9APDE5ACYP3A4ALOX5APFEN1 | |
| SCHEMBL31309284 | 0.86 | SCN9A (0.46) | SCN9ACYP3A4ALOX5APFEN1CYP1A2 | |
| SCHEMBL31309258 | 0.85 | PDE5A (0.46) | SCN9APDE5AALOX5APFEN1 | |
| SCHEMBL24379596 | 0.84 | SCN9A (0.40) | SCN9APDE5A | |
| SCHEMBL31309249 | 0.84 | SCN9A (0.46) | SCN9ACYP3A4ALOX5APFEN1CYP1A2 | |
| SCHEMBL30214805 | 0.84 | SCN9A (0.39) | SCN9APDE5ACYP3A4 | |
| SCHEMBL30214803 | 0.84 | SCN9A (0.39) | SCN9APDE5ACYP3A4 | |
| SCHEMBL30108760 | 0.83 | MAOA (0.37) | SCN9APDE5A | |
| SCHEMBL27354709 | 0.82 | CYP11B1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735433-A2 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF | Viva Star Biosciences (US) Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006681-A2 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS INHIBITORS OF NLRP3 ACTIVITY AND THERAPEUTIC USES THEREOF | VIVA STAR BIOSCIENCES (US) INC. (US) | 2025-01-02 | — | — | WO | disclosed |