Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888510 | 1.00 | KMT2A (0.55) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL31387020 | 1.00 | KMT2A (0.55) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL3087950 | 0.92 | KMT2A (0.58) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL7855942 | 0.84 | KMT2A (0.69) | KMT2AEPHX2CASP3 | |
| SCHEMBL6187733 | 0.82 | KMT2A (0.65) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL25390706 | 0.82 | KMT2A (0.52) | KMT2AEPHX2CASP3 | |
| SCHEMBL25391589 | 0.82 | KMT2A (0.52) | KMT2AEPHX2CASP3 | |
| SCHEMBL16942065 | 0.82 | KMT2A (0.52) | KMT2AEPHX2CASP3 | |
| SCHEMBL30748702 | 0.82 | KMT2A (0.52) | KMT2AEPHX2CASP3 | |
| SCHEMBL3060297 | 0.81 | KMT2A (0.51) | KMT2AEPHX2CASP3FABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025032254-A1 | ANTHRACYCLINE DERIVATIVES AND CONJUGATES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-02-13 | — | — | WO | disclosed |