Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 9/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31311348 | 0.91 | MPL (0.42) | BRAFTRPV4ALDH1A1PKMLCK | |
| SCHEMBL31311213 | 0.84 | LCK (0.45) | BRAFALDH1A1PKMLCKCYP17A1 | |
| SCHEMBL31311393 | 0.83 | PLTP (0.46) | BRAFALDH1A1PKMLCKCYP17A1 | |
| SCHEMBL31311252 | 0.82 | BRAF (0.41) | BRAFALDH1A1PKMLCKCYP17A1 | |
| SCHEMBL31311359 | 0.78 | BRAF (0.39) | BRAFALDH1A1PKMLCKCYP17A1 | |
| SCHEMBL31311238 | 0.77 | PLTP (0.51) | ALDH1A1LCKCYP17A1 | |
| SCHEMBL31311376 | 0.76 | ADORA2A (0.52) | ALDH1A1PKMLCKCYP17A1MEN1 | |
| SCHEMBL31311339 | 0.75 | PLTP (0.44) | BRAFALDH1A1PKMLCK | |
| SCHEMBL31311210 | 0.74 | LCK (0.45) | BRAFALDH1A1PKMLCKCA1 | |
| SCHEMBL31311281 | 0.73 | MEN1 (0.58) | ALDH1A1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731206-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | Veralox Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024264032-A2 | COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES | VERALOX THERAPEUTICS INC. (US) | 2024-12-26 | — | — | WO | disclosed |