Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17492384 | 0.81 | PDE4A (0.76) | PDE4APTGS1PTGS2PDE4BPDE4D | |
| SCHEMBL17492366 | 0.81 | PDE4A (1.00) | PDE4APTGS1PTGS2PDE4BPDE4D | |
| SCHEMBL9893269 | 0.79 | PTGS1 (0.60) | PDE4APTGS1PTGS2PDE4BGAA | |
| SCHEMBL17508883 | 0.79 | PDE4B (0.50) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL2067935 | 0.76 | PDE4A (0.67) | PDE4APTGS1PTGS2PDE4BPDE4D | |
| SCHEMBL2066273 | 0.76 | PDE4A (0.67) | PDE4APTGS1PTGS2PDE4BPDE4D | |
| SCHEMBL9923880 | 0.75 | PTGS1 (0.58) | PDE4APTGS1PTGS2PDE4BGAA | |
| SCHEMBL25527779 | 0.74 | PDE4A (0.65) | PDE4AGAACYP1A2ALDH1A1MAPT | |
| SCHEMBL17492367 | 0.74 | PDE4B (0.69) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL17492380 | 0.71 | PDE4B (0.64) | PDE4APTGS1PTGS2PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929708-B | 4- [ [ (7-Aminopyrazolo [1,5-a ] pyrimidin-5-yl) amino ] methyl ] piperidin-3-ol compounds and their therapeutic uses | 卡里克治疗有限公司 | 2025-02-18 | — | — | CN | disclosed |