Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22065262 | 0.83 | DRD3 (0.47) | DRD3P4HTMALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL29601112 | 0.81 | GSK3B (0.56) | DRD3P4HTMALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL27039929 | 0.81 | DRD3 (0.46) | DRD3P4HTMALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL21484711 | 0.81 | GSK3B (0.56) | DRD3P4HTMALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL22257011 | 0.80 | KDM4E (0.53) | ALDH1A1L3MBTL1CYP1A2HPGDATM | |
| SCHEMBL31312576 | 0.80 | MAOB (0.50) | ALDH1A1L3MBTL1MAPK1MAPTRAB9A | |
| SCHEMBL29514365 | 0.80 | MAPK1 (0.41) | P4HTMALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL30785982 | 0.80 | KDM4E (0.53) | ALDH1A1L3MBTL1CYP1A2HPGDATM | |
| SCHEMBL29049994 | 0.80 | MAPK1 (0.41) | P4HTMALDH1A1L3MBTL1MAPK1KDM4E | |
| Bromide SCHEMBL27039939 | 0.80 | GSK3B (0.54) | DRD3P4HTMALDH1A1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705296-A1 | HETEROARYLINDOLE INHIBITORS OF APOL-1 | OmniAB, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024242846-A1 | HETEROARYLINDOLE INHIBITORS OF APOL-1 | OMNIAB, INC. (US) | 2024-11-28 | — | — | WO | disclosed |